STM Article Repository

The intention of the present study is to evaluate the toxic effects of a hybrid pesticide (i.e. combination of two classes of pesticides), Chlorpyrifos 50% + Cypermethrin 5% EC (Organophosphate + Synthetic Pyrethroid) on the liver and ovary of an air breathing fish, Clarias batrachus exposed to the sub- lethal concentration. The study revealed histopathological changes in the liver which include irregular hepatocytes, nuclear hypertrophy, cytoplasmic vacuolation and glycogen depletion etc. Histopathological changes observed in the ovary included oocyte shrinkage, oocyte degeneration, destruction of ovigerous lamellae and cytoplasmic necrosis etc. These observations are considered as an indicative of the toxic effects caused by this hybrid pesticide at cellular/histological level in the organs of the fish, Clarias batrachus.