STM Article Repository

At the present time, only few reports including systematic reviews of malignant peripheral nerve
sheath tumors (MPNSTs) with spinal involvement have been existed. According to few reports as well
as scant review literatures have been existed [1,2,3,4], the MPNSTs with spinal involvement are still
considered as an infrequent topic. Although there were reports of both MPNSTs of paraspinal soft
tissue (type 1) resulting in secondary vertebral destruction and MPNSTs primarily originated from
intraosseous of vertebra itself (type 2), these kinds of tumors are exceptionally rare.
In this present report, we hereby demonstrated a case of type 2 MPNSTs which is not related to
neurofibromatosis type 1 (NF 1) occurring in the thoracic spine and reviewed the clinical, radiologic,
and pathologic as well as shared part of our experience in treating this rare condition. From our
review, to date, total en bloc spondylectomy could be the treatment of choice for the selected case of
the spinal MPNSTs. Posterior-only approach can be performed safely with a delicate preoperative
surgical planning and management in selected patient. Interestingly, MPNSTs usually have a high
rate of recurrence both local and metastasis even in the cases of successful en bloc resection with
adjuvant therapy, but not in ours for 5-year follow up.