STM Article Repository

Infective endocarditis (IE) refers to infection of the endocardial surface of the heart. Uremia can be an initial manifestation of IE. In a patient presenting with acute renal failure (ARF), asymptomatic pansystolic murmur resulted in diagnosis of IE. Severe mitral regurgitation (MR) and large vegetation were found in echocardiographic examination. Following antibiotic therapy renal function improved. Due to large vegetation and perforation on the mitral valve, patient was operated for mitral valve replacement. Postoperative period was uneventful. On last examination, he had nephrotic range proteinuria. In this paper IE and renal lesions were discussed. We would like to pay attention to the fact that in the absence of fever and positive blood cultures, endocarditis can develop and cause serious clinical signs.