STM Article Repository

Chronic energy imbalance is a strong predictor of metabolic abnormalities; a sizable number of research has been carried out to investigate how this system of obesity and energy homeostasis are understood, its metabolic consequences, and possible solutions to restore homeostasis. Currently, there is an array of methodologies designed for measurements of various aspects of energy metabolism. It is exigent therefore to understand the relative merits of each methodology in order to choose the most appropriate ones for research and other investigations. It is also important to note that studies of this nature require precision and accuracy. In this review article, we provide information on the utility and limitations of methodologies that are commonly used in energy expenditure research, with a specific focus on its variability, correlations, indications and contraindications.