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The experiment was conducted at SIF of Chandra Shekhar Azad University of Agriculture & Technology, Kanpur during Rabi season of 2017-18. It was experiment consisted eight treatments of different nutritional doses of micro nutrient, organic manure, and micro-organisms, along with major nutrient with the objective to find out the effect of vermicompost, FYM, Azotobacter, PSB with chemical fertilizer on growth, treatment combination for wheat and assess the economics of the treatments. Due to balance nutrition in wheat variety Shekhar (K-1006). The experiment was organized under RBD with three replications. It was the soil of the field Analyzed medium fertility status concerning available NPK, S and Zn status of micronutrients. The treatment T5 (RDF + Azotobacter + PSB + vermicompost @ 5 t ha-1) found superior in terms of maximum root and shoot growth, yield attributes and yield the maximum grain yield (58.75 q/ha.), under recorded in T5 (RDF + Azotobacter + PSB + vermicompost @ 5 t ha-1) treatment compared to control treatment.